Nutrend Curcumin Bioperine® + Vitamin D - 60 CapsNutrend Curcumin Bioperine® + Vitamin D is a dietary supplement designed to support overall health by combining the potent anti-inflammatory properties of curcumin with the enhanced absorption power of Bioperine® and the powerful immune-boosting effects of vitamin D. This supplement is ideal for individuals seeking to reduce chronic inflammation, support joint and muscle health, improve immune function, and enhance nutrient absorption. It is intended for people who lead active lives, have inflammatory diseases, or are simply health-conscious. A unique formula of three active substances that represents an ideal product for detoxes. The extract from curcuminoids has antioxidant effects, is anti-inflammatory, and supports proper digestion and immunity. Thanks to the unique combination of the patented black pepper extract and vitamin D, it is up to 185 times more absorbable than natural curcumin.   Turmeric extract (Curcumin) exhibits a significant antioxidant effect according to study results. It is often used in inflammatory conditions or in detoxification regimens. Curcumin is the principal active compound in turmeric (Curcuma longa), a plant long used in traditional medicine. Curcumin exhibits strong anti-inflammatory, antioxidant, antimicrobial, and anticancer properties. It functions by modulating numerous signalling molecules, including inflammatory cytokines, transcription factors like NF-κB, enzymes like COX-2 and iNOS, and growth factors. Curcumin helps inhibit the production of pro-inflammatory molecules such as tumour necrosis factor-alpha (TNF-α), interleukins (IL-1, IL-6), and prostaglandins, which are often elevated in chronic inflammatory diseases such as arthritis, metabolic syndrome, and cardiovascular disorders. It also promotes oxidative balance by scavenging free radicals and enhancing the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase. However, regular consumption of curcumin suffers from poor natural bioavailability due to rapid metabolism in the liver and intestinal wall, limited absorption, and systemic elimination.   Vitamin D contributes to the normal function of the immune system and helps to maintain normal muscle functions. The body synthesises it from sunlight. Many immunologists recommend supplementing it regularly. Vitamin D is a fat-soluble secosteroid that plays a crucial role in calcium and phosphorus homeostasis and bone mineralisation. Vitamin D regulates gene expression in over 1,000 genes and has effects far beyond bone health. It enhances immune responses by promoting the activity of macrophages and dendritic cells while modulating the adaptive immune system by shifting T cell responses toward anti-inflammatory phenotypes (increased Treg and Th2 activity, reduced Th1 and Th17). Deficiency in vitamin D has been linked to increased susceptibility to infections, autoimmune disorders, muscle weakness, osteoporosis, and mood disturbances. Given that many people have suboptimal vitamin D levels due to limited sun exposure, especially in northern latitudes or during winter, supplementation is often found to be necessary.   BioPerine® is the only piperine product that achieved patented status for its ability to increase the biological availability of nutrients. Bioperine® is a patented extract obtained from black pepper fruits (Piper nigrum) standardised to contain 95% piperine. Piperine is an alkaloid that significantly enhances the bioavailability of various nutrients, such as curcumin. It achieves this through several mechanisms: inhibition of hepatic and intestinal glucuronidation (a metabolic pathway that makes curcumin water-soluble for excretion), increased thermogenesis (raising internal temperature to enhance solubility and transport across membranes), and modulation of efflux mechanisms like P-glycoprotein, which normally pumps compounds like curcumin out of cells. Clinical studies have shown that co-administration of Bioperine® with curcumin increases curcumin's bioavailability by up to 2000%, making it significantly more effective at lower doses.   Nutrend Curcumin Bioperine® + Vitamin D is particularly beneficial for individuals experiencing joint stiffness, muscle soreness, or systemic inflammation, such as those with arthritis, inflammatory bowel disease, or metabolic syndrome. The curcumin component helps modulate inflammatory pathways and oxidative stress, making it suitable for those managing pain, swelling, or recovery from physical activity or injury. People with weakened or compromised immune systems, frequent infections, or those prone to seasonal illnesses can benefit from the vitamin D in the formula, which enhances immune cell function and supports resistance to pathogens. It is also valuable for individuals living in areas with limited sunlight, who may not produce adequate vitamin D naturally. For people with poor nutrient absorption, such as those with gastrointestinal disorders like Crohn’s disease or coeliac disease, Bioperine® improves the bioavailability of curcumin and other nutrients by enhancing gastrointestinal absorption and reducing metabolic loss.   Nutrend Curcumin Bioperine® + Vitamin D is also suitable for individuals interested in healthy ageing, cognitive protection, and cardiovascular wellness due to the neuroprotective and anti-inflammatory roles of curcumin and the hormone-like effects of vitamin D in regulating calcium metabolism and vascular integrity. Altogether, Nutrend Curcumin Bioperine® + Vitamin D offers a synergistic formula designed to optimise absorption and efficacy, targeting systemic inflammation, immune regulation, and skeletal health. It is suitable for anyone looking to proactively support their long-term health, particularly those managing chronic inflammation, joint pain, immune imbalances, or nutrient absorption concerns.   Supplement Facts:Servings per container: 60Serving size: 1 capsule   Amount per serving:NovaSOL® Curcumin mixture 500 mgCurcuminoids 30 mg- of which curcumin 25 mgVitamin D 7 µgBlack pepper extract 1,1 mg   Ingredients:NovaSOL® (emulsifier polysorbate 80, turmeric extract (6 % of curcuminoids), cholecalciferol), hydroxypropyl methylcellulose capsule, antioxidant ascorbic acid, black pepper extract (95 % of piperine) – BioPerine®.   Recommended Use:Take 1-2 capsules daily with food. Drink plenty of water.

NUTREND FLEXIT DRINK - 400 g FLEXIT drink protects, nourishes and regenerates tissue - joints, joint capsules, cartilage, tendons, ligaments and bone. Collagen protein (hydrolysed gelatin) a source of a wide range of amino acids and peptides which are involved in the formation of collagen. Ensure proper development, nourishes and protects the joint. It improves the condition of hair, skin and nails. The formulation uses 97% enzymatically hydrolyzed gelatin grafted with high biological value, easy to digest, łatwowchłanialny and immediately used by the body. Glucosamine is formed in the body from glucose. Positive influence on the mobility of joints and stimulates the synthesis of connective tissue. Limits the catabolic processes within the cartilage. Involved in the formation of synovial fluid in the joints allow movement, and protect basic elements before traction. Glucosamine is a precursor to chondroitin. Chondroitin sulfate builds and regenerates tissue. Ensuring the appropriate level by complementing diet intensely protects against degeneration of cartilage, which research has shown. Hyaluronic acid is a major component of synovial fluid intercellular mass of cartilage. Adds softness, elasticity and viscosity. The structure of the molecule has the properties of hyaluronic acid, even at low concentrations, many of the binding of water molecules during gel formation, increasing tissue resistance to external pressure. MSM (methylsulfonylmethane) is an organic sulfur compound that occurs naturally in the human body. It is involved in the formation of collagen fiber structure. Due to its antioxidant properties damaged cartilage protects against free radicals, while reducing pain. Sulfur in MSM is involved in the synthesis of the essential amino acids L-methionine and L-cysteine. L-Proline is essential for the formation of collagen, accelerates regeneration of damaged cartilage and ligaments. Vitamin C is an antioxidant. Eliminates free radicals, which damage the surface of cartilage. Vitamin D3 increases the saturation of bone calcium. Calcium is the primary building block of bone. Magnesium in combination with calcium affects the nervous system and the musculoskeletal. Works anti-stress on the body. Supplement Facts: Serving Size: 1 Scoop (20g) Serving Per Container: 20 Amount Per Serving: Calories 65.8 kcal Protein 10.2 g Carbohydrates 5.8 g Fat 0 g Calcium 92 mg magnesium 55mg Vitamin C 100 mg Vitamin B6 5 mg Vitamin D3 7.5 mcg glucosamine sulphate 300 mg chondroitin sulfate 150 mg L-proline 500 mg methylsulfonylmethane (MSM) 300 mg Hyaluronic acid (sodium salt) 20 mg Collagen protein 10000 mg Recommended Use: Maintenance of healthy joints: Take half of serving (10 g) a day in the morning on an empty stomach. If Increased load and degenerative tissue disorders: Take 1 serving (20 g) per day in the morning on an empty stomach. Pour the recommended amount of powder to a small amount of still water, mix and make up to the required volume. Ratio is 20 g to 250 ml of water. Visible gel particles, which produces hyaluronic acid is a natural feature of the product.